1. Omicron:

The Omicron variant of COVID-19 has remained called a variant of fear by WHO based on the sign that it has several mutations that may have an influence on how it acts. There is consistent evidence that Omicron is spreading significantly faster than the Delta variant in countries with documented community transmission, with a replication time of 2-3 days. The overall risk allied to this new variant remains very high.

When a virus is circulating extensively and triggering numerous infections, the likelihood of the virus mutating increases. The more opportunities a virus has to spread, the more chances it has to undergo changes. New variants like Omicron are a cue that the COVID-19 pandemic is far from over. It is therefore essential that publics get the vaccine when accessible to them and continue to follow existing advice on preventing the spread of the virus, including physical distancing, Wearing masks, regular hand wash and keeping indoor areas well ventilated. It is also crucial that vaccines and other community health measures are accessible everywhere.

2. COVID-19 Drug design and Development:

COVID-19 is a devastating respiratory and inflammatory illness caused by a new coronavirus that is speedily spreading throughout the global population. SARS-CoV-2 is the virus that causes COVID-19. A debilitating disease publicly, economically and biologically, COVID-19 converted a pandemic in 2020. Research in the Drug Discovery, Design and Optimization for Novel Therapeutics Laboratory is designed to attack the virus at critical progression stages. First, we target to block the virus since binding to the cell. Second, we endeavour to block the virus from gaining admission into the cell. And third, we seek to block the virus from replication within any infected cells concluded using a combination of drugs targeting all three of those stages, simultaneously.

The threefold goal is to:

• Prevent binding of virus to its cell external receptor
• Block membrane union of the virus via the endosomal pathway
• Stop viral replication by averting the main protease (Mpro) from creating the proteins needed to assemble additional viral particles

3. COVID-19 Clinical Trails:

Clinical trials are medical research studies with volunteers. The purpose of the studies is to determine whether a new treatment or vaccine works and is safe for persons to use. This learning is a randomized, double-blinded, multi-center, Placebo-controlled phase III clinical trial in adults aged 18-59 years. The purpose of this study is to evaluate the efficacy, security, and immunogenicity of the experimental SARS-CoV-2 inactivated vaccine. The investigational vaccine and placebo were both manufactured by Sinovac Research & Development Co., Ltd. A total of 13.000 matters will be enrolled. Participants will be allotted to receive two doses of experimental vaccine or placebo on the schedule of days 0, 14. It is planned that the study will be led by two separate cohorts. The first cohort will be healthcare workers in the high-risk group and the second cohort will be people at normal risk.

As part of the reaction to the COVID-19 pandemic, NIAID is leading and supporting clinical research to prevent, treat, and better understand respiratory illness. These efforts are made possible by the substantial contributions of clinical research helpers and are complemented by additional clinical research studies across the world. They include clinical trials evaluating therapeutics and vaccine candidates against SARS-CoV-2, The novel coronavirus that causes COVID-19, as well as studies of people who have recovered from infection.

4. COVID-19 and Environmental Health:

Modern lifestyle may negatively affect our health. As a result, several people may be in a disadvantageous location to face the pandemic with an already impaired immune system due to their exposure to environmental health hazards. Humans are in constant exposure—willingly or not—to various Endocrine-disrupting chemicals, Mutagens, carcinogens, hazardous radiation, and psychological pressure aspects that interact with their immune system.  Additionally, food and water safety issues, climate change, as well as water, soil, and air pollution are only a few environmental factors with recognized detrimental effects on human and animal health.

Precautions for COVID-19:

Protect yourself and others around you by knowing the truths and taking suitable precautions. If you have a Fever, Cough, and Struggle breathing, seek medical attention. Call in advance so your healthcare provider can straight you to the right health facility. This shields you and stops the spread of diseases and other infections.

5. Infectious disorders:

Infectious diseases are illnesses caused by organisms — such equally Bacteria, Viruses, Fungi, or parasites. Numerous organisms live in and on our bodies. They're normally harmless or even helpful. But under certain circumstances, some organisms might cause disease. Some infectious viruses can be passed from person to somebody.

Bacteria - one-celled germs that multiply quickly. They can give off poisons, which are damaging chemicals that can make you sick. Strep throat and urinary tract infections are joint bacterial infections.

Viruses - tiny capsules that contain genetic material. They enter your cells so that they can multiply. This can kill, mutilate, or modify the cells and make you sick. Viral impurities include HIV/AIDS and the common cold.